Protransit

ProTransit is commercializing Pro-MP™ a patented, sustained-release microparticle

A drug delivery platform that penetrates the skin to deliver a wide range of pharmaceutical actives

potentially better, faster, and safer than needles and pills.

Crow's feet improvement in as early as 5 weeks.

Biopsy of the crows' feet area: unprecedented doubling of the dermis in 3 months.

Biopsy of the crows' feet area: significant improvement in the synthesis of collagen and elastin

Improvements in redness and dyschromia in 4 months.

Reduction in subcutaneous sun spots in 4 months.

Baseline

Day 60

Day 120

Baseline

MONTH 3: UP TO 4X MORE HAIR THAN ROGAINE AT 1 YEAR AND UP TO 3X MORE HAIR THAN PROPECIA (FINASTERIDE) AT 2 YEARS

A new Approach to drug delivery Backed By Science

Pro-MP™ microparticles releasing superoxide dismutase (SOD) and catalase (CAT) antioxidants. Diameter: approximately 200 billionths of a meter. Particle release: up to 192 hours

10 Years of Innovation:

Based on 10+ years of research at the University of Nebraska Medical Center, Creighton University School of Medicine and USC Keck School of Medicine, ProTransit has developed Pro-MP™, a unique, patented, sustained-release microparticle drug delivery technology shown to penetrate the skin, scalp, eye, and mucosal tissues to deliver active ingredients.

Pro-MP may also be IV-administered. R&D continues to explore exciting new formulations with Pro-MP that deliver ingredients to treat diseases with unmet needs for better clinical outcomes.

The Challenge:

Active ingredients in topically applied products rarely penetrate the skin. Another hurdle is getting active ingredients to be slowly released locally with minimal systemic uptake. Keeping actives local may help lower the risk of body-wide side effects and can provide benefits such as higher doses that are typically difficult to achieve through oral administration.

The Solution:

Using Pro-MP, a unique and effective ingredient delivery technology to:

• Penetrate the skin and slowly release pharmaceutical active ingredients locally for up to 192 hours, with minimal systemic uptake
• Deliver powerful antioxidants into the skin 24/7 to neutralize free radicals and optimize skin health and appearance
• Target the hair follicle directly to stimulate hair regrowth and improve hair quality